This book presents a synopsis of the theoretical principles and practical experience concerning the interfacial behavior of bioproducts. Comprehensive coverage ranges from the fundamentals of bioproduct and solid surface structure to the interactions of multicomponent mixtures in heterogeneous systems.

From the Preface: “Bioprocesses typically involve multicomponent systems, with tissue cells, microbes, proteins (including glycoproteins and lipoproteins), polysaccharides, and smaller molecular species, all dissolved or suspended in an aqueous fluid. The macromolecular and cellular `bioproducts' in such processes are amphipathic and usually prefer to exist at interfaces...”

Target Audience: Scientists, technologists, engineers, and other professionals in the biotechnology and medical devices industries.

Table of Contents:

The Role of Interfacial Phenomena in Biotechnology: An Overview

Modern Theory and Methods:

Proteins at Interfaces: Principles, Problems, and Potential

Surfaces in Biology and Biomaterials: Description and Characterization

Physics of Solid Surfaces

Thermodynamics of Protein Adsorption

Theoretical Models for Polymer Adsorption

Statistical Mechanics of Protein Adsorption

Transport and Adsorption of Cells and Proteins at Interfaces

Spectroscopic and Other Techniques for Studying Adsorption of Bioproducts at Interfaces

Some Methodological Aspects of the Wettability Gradient Method

Some Applications and Current Research:

Bioactive Peptides and Surface Design

Immobilized Enzymes and Cells

Cell Culturing: Surface Aspects and Considerations

Proteins on the Surfaces of Food Emulsions: Adsorption, Structure, and Emulsion Stability

Cell—Surface Interactions: The Blood Platelet as Paradigm

Index