This book provides quick and easy solutions to 45 typical questions posed by HPLC users, with coverage of simple equipment tests, selection criteria for columns, buffers, etc., and options for optimizing separations. Practical Problem Solving in HPLC also features a special chapter on the separation of ionic compounds on RP material by R. LoBrutto and Y. Kazakevich. It is a first-aid kit for every HPLC user.

From the Preface: “...[These] ‘tips’ are all about fast answers and help. At the same time, they try to point out connections and give explanations in compact form. Language, style and construction of the book serve only one purpose: to make it an easy-to-read companion in the HPLC laboratory. It should not be thought of as a textbook. The reader should acquire the basics of HPLC from the literature on the subject...“

Target Audience: Everyone who needs to improve proficiency in HPLC.

Table of Contents:

Introduction

Simple Tests and Decision Criteria

Problems and Their Solutions

Tips to Optimize the Separation

Retention of Ionizable Components in Reversed-Phase HPLC

Appendices

Index