Solvents have been the cause of occupational health problems for as long as they have been used — workers have been exposed through skin contact, by breathing vapors and, in extreme cases, by ingestion. This book examines the clinical consequences of exposure to different solvents, with a strong focus on the workplace.

In Toxicology of Solvents, the authors distill their examination of material from key medical and toxicological libraries, books, databases and their own case studies, presenting a well-organized reference work on the key effects of solvent exposure. The information is summarized in ordered sections, including carcinogenicity, skin and eye exposure effects, inhalation effects, reproductive effects, and potential genetic effects. Both acute and chronic exposures are reviewed.

From the Introduction: “The chapters in this book contain an overview of the toxicity of a number of individual solvents or, in the case of glycol ethers and their acetates, a group of solvents. The emphasis is on occupational exposure, although not exclusively so, as examples and information are drawn from other areas. Definitions of some of the terms used are given in the glossary. Each chapter has the same layout...”

Target Audience: Medical professionals, industrial health and hygiene specialists, and others concerned with the toxicology of solvents.

Table of Contents:

Introduction

Acetone

Benzene

Carbon Disulphide

Carbon Tetrachloride

Chloroform

Diacetone Alcohol

Diisobutyl Ketone

N,N-Dimethylformamide (DMF)

Ethanol

Ethyl sec-Amyl Ketone

Glycol Ethers and Esters

Hexane/n-Hexane

Isopropanol

Methanol

Methylene Chloride

Methyl n-Butyl Ketone (MnBK)

Methyl Ethyl Ketone (MEK)

Methyl Isobutyl Ketone (MIBK)

N-Methyl-2-Pyrrolidone (NMP)

Tetrachloroethylene

Toluene

1,1,1,-Trichloroethane (1,1,1-TCE)

Trichloroethylene

White Spirit

Xylenes

Index