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This book considers how exposure to toxic mixtures affects the different physiological systems
and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous,
and reproductive systems, as well as the various organs, including the kidneys, liver, and skin. It
evaluates various sources of exposure, including air, water, and soil pollution;
in utero exposure; chemicals contained in foods, cosmetics, and domestic cleaning products; adhesives and paints; industrial
chemicals; pesticides; electromagnetic radiation; and chemicals ingested or inhaled through the use
of alcohol, tobacco, and narcotics.
From the Preface: “...A review of the literature revealed many examples of unexplained health
effects on humans following exposures to mixtures. A study of these showed that in every unexplained
instance the mixture contained at least one lipophilic (fat soluble) and one hydrophilic (water
soluble) chemical. The literature showed that all body tissues have lipophilic barriers surrounding them.
This suggested that absorption of lipophilic chemicals should occur more easily than for hydophilic
species. This too was confirmed by the literature and it was then hypothesized that lipophiles facilitate
the absorption of admixed hydrophiles...”
Target Audience: Toxicologists, industrial hygienists, chemical formulators, medical practitioners,
and other professionals concerned with the toxicology of chemical mixtures.
Table of Contents:
Introduction to Chemical Toxicology of Mixtures:
Introduction
Health Effects of Exposures to Chemical Mixtures
Absorption of Chemical Mixtures
Chemical Toxicology
Exposures to Chemical Mixtures:
Scope and Sources of Toxic Exposures
In Utero Exposures
Air Pollution
Water Pollution
Soil Pollution
Food
Chemicals in and Around the Home
Sick Building Syndrome
Industrial Exposure
Pesticides
Alcohol and Tobacco: Recreational Toxins
Electromagnetic Radiation and Toxic Exposure
Mixture Effects on Body Systems:
Respiratory System
Nervous System
Developmental Neurotoxicology
Autism: Effect of Maternal Exposure to Neurotoxic Chemicals
Attention Deficit Hyperactivity Disorder (ADHD)
Endocrine System
Toxic Infertility
Teratogens
Immune System
Chemical Sensitivity: Multiple Chemical Sensitivity (MCS), Chronic Fatigue Syndrome
(CFS), Fibromyalgia (FM), and Gulf War Syndrome (GWS)
Skin
Musculoskeletal System
Cardiovascular System
Liver
Kidneys
Cancer
Childhood Cancer
Cancer Clusters
Regulatory Requirements and Conclusions:
Regulatory Requirements
Conclusions and Recommendations
Index
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