This book provides in-depth guidance on all aspects of quality assurance and measurement results produced in analytical chemistry laboratories. The range of coverage offers an integrated view on measures like the use of reference materials and method validation. The discussion includes often misunderstood topics such as uncertainty and traceability. A CD-ROM with Excel datasheets accompanies the text, allowing users to develop and customize models appropriate for specific laboratory operations. The presentation of underlying theory, combined with the hands-on opportunities afforded, provides the reader with a fundamental understanding, along with the ability to apply it to real world examples.

From the Preface: “...The theoretical part of the book contains information on questions relating to quality control systems. The practical part includes more than 60 examples relating to validation parameter measurements, using statistical tests, calculation of the margin of error, estimating uncertainty, etc. For all examples, a constructed datasheet (Excel) is attached, which makes problem solving easier. The accompanying CD includes more than 60 Excel datasheet files, each consisting of three main components: problem, data, and solution; in some cases, additional data such as graphs and conclusions are also included. After saving an Excel file on the hard disk, it is possible to use it on different data sets...”

Target Audience: Analytical and pharmaceutical chemists, chemical engineers, and students of these disciplines.

Table of Contents:

Basic Notions of Statistics

Quality of Analytical Results

Traceability

Uncertainty

Reference Materials

Interlaboratory Comparisons

Method Validation

Appendix

Index